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secobarbital will lessen the extent or effect of lapatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.secobarbital will decrease the level or effect of budesonide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.Caution must be exercised when Seconal Sodium (secobarbital sodium c